One thing that transphobes seek is retention of the status quo (in this case, that men are men and women are women). The anti-trans lobby is fighting a bifrontal war which is entirely unjustified. Here's something worthy of note. The filthy grub who claims that Joe Biden's trans policies are cruel is the same filthy grub who boasted of "grabbing women by the p***y." That is male entitlement.

What male anti-trans supporters of that grub need to consider, if they have the capacity is that when people lament the "brain drain" they are talking about losing talented people to other organisations or other countries. Anti-trans males are not losing allies if people assigned male at birth transition, as they don't think like them in the first place.

In answer to your question, however, a trans person does not feel comfortable with the roles to their assigned sex.